Agminated blue naevi in a patient with EMO syndrome.

© 2013 The Authors. doi: 10.2340/00015555-1366 Journal Compilation © 2013 Acta Dermato-Venereologica. ISSN 0001-5555 The triad exophthalmus, pre-tibial myxoedema, osteoarthropathia (EMO syndrome) was first described by Thomas in 1933 and represents a rare condition occurring in patients with Graves’ disease (1). Graves’ disease is a common autoimmune disorder of the thyroid gland due to a production of autoantibodies mainly directed against the thyrotropin (TSH) receptor. In less than 1% of affected patients, the triad of endocrine ophthalmopathy, myxoedema and osteoarthropathy successively occurs in the course of the disease (2–4). We describe here a case of EMO syndrome with agminated blue naevi at both temples suggestive for a Carney complex. Individuals affected by a Carney complex typically present with cardiac and cutaneous myxomas, endocrinopathy, lentiginosis and endocrine and non-endocrine neoplasia (5).